Former national security advisor Susan Rice has expressed strong criticism of the agreement signed with Iran. She considers it a significant mistake in terms of national security, describing it as the largest error in decades. Her comments also characterized the negotiated memorandum of understanding with Iran in harsh terms, emphasizing its negative aspects.

According to Rice, the document is astounding and horrible, implying a surrender. Further details on Rice's statement can be found in La Opinión, which reported her remarks on the Iran agreement.